Molecule Details
| InChIKey | ZJAOAACCNHFJAH-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | O=C(O)P(=O)(O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.1 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB00529 |
|---|---|
| Drug Name | Foscarnet |
| CAS Number | 4428-95-9 |
| Groups | approved investigational |
| ATC Codes | J05AD01 |
| Description | An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV. |
Categories: Acetates Acids, Acyclic Anti-Infective Agents Anti-Retroviral Agents Antiinfectives for Systemic Use Antiviral Agents Antivirals for Systemic Use Chelating Activity Direct Acting Antivirals Enzyme Inhibitors Nephrotoxic agents Nucleic Acid Synthesis Inhibitors OAT1/SLC22A6 inhibitors Organophosphonates Organophosphorus Compounds Phosphonic Acid Derivatives Potential QTc-Prolonging Agents Pyrophosphate Analog DNA Polymerase Inhibitor QTc Prolonging Agents Reverse Transcriptase Inhibitors
Cross-references: BindingDB: 50011181 ChEBI: 127780 CHEMBL666 ChemSpider: 3297 Drugs Product Database (DPD): 902 C06456 D00579 PDB: PPF PharmGKB: PA449706 PubChem:3415 PubChem:46507873 RxCUI: 33562 Therapeutic Targets Database: DAP001383 Wikipedia: Foscarnet ZINC: ZINC000008101109