Molecule Details
| InChIKey | ZIWQBCKDJZBDIR-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-methyl-4-[4-[(4-piperidin-1-ylpyrimidin-2-yl)amino]phenoxy]pyridine-2-carboxamide |
| Canonical SMILES | CNC(=O)c1cc(Oc2ccc(Nc3nccc(N4CCCCC4)n3)cc2)ccn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.14 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49116 | NR2C2 | Homo sapiens | Human | PF00104 PF00105 | 6.2 | IC50 | ChEMBL |
| Q15750 | TAB1 | Homo sapiens | Human | PF00481 | 6.2 | IC50 | ChEMBL;BindingDB |
| P19838 | NFKB1 | Homo sapiens | Human | PF12796 PF00531 PF16179 PF00554 | 6.1 | IC50 | ChEMBL |
| Q00653 | NFKB2 | Homo sapiens | Human | PF00023 PF12796 PF00531 PF16179 PF00554 | 6.1 | IC50 | ChEMBL |
| Q04206 | RELA | Homo sapiens | Human | PF16179 PF00554 | 6.1 | IC50 | ChEMBL |