Molecule Details
| InChIKey | ZISLJLXCLUQNKA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[4-[4-[(4-Aminocyclohexyl)amino]-2-[3,5-bis(trifluoromethyl)anilino]pyrimidin-5-yl]pyrazol-1-yl]ethanol |
| Canonical SMILES | NC1CCC(Nc2nc(Nc3cc(C(F)(F)F)cc(C(F)(F)F)c3)ncc2-c2cnn(CCO)c2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.65 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q06418 | TYRO3 | Homo sapiens | Human | PF00041 PF07679 PF07714 | 8.5 | IC50 | ChEMBL;BindingDB |
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 8.0 | IC50 | ChEMBL;BindingDB |
| P30530 | AXL | Homo sapiens | Human | PF00041 PF13927 PF07714 | 6.4 | IC50 | ChEMBL;BindingDB |