Molecule Details
InChIKeyZHTVWJDQZBBZHV-UHFFFAOYSA-N
Compound Name5-(3-Phenylmethoxyphenyl)-7-(4-pyrrolidin-1-ylcyclohexyl)pyrrolo[2,3-d]pyrimidin-4-amine
Canonical SMILESNc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2C1CCC(N2CCCC2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.47
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.5 Ki ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.9 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.4 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.4 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.2 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.2 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.1 Ki ChEMBL