Molecule Details
| InChIKey | ZHJNDQAMSAUBBB-UHFFFAOYSA-N |
|---|---|
| Compound Name | [5-amino-1-(2-methyl-6,7-dihydro-1H-benzimidazol-5-yl)pyrazol-4-yl]-[5-[(4-methylsulfonylpiperazin-1-yl)methyl]-1H-indol-2-yl]methanone |
| Canonical SMILES | Cc1nc2c([nH]1)CCC(n1ncc(C(=O)c3cc4cc(CN5CCN(S(C)(=O)=O)CC5)ccc4[nH]3)c1N)=C2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.83 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 8.1 | IC50 | ChEMBL;BindingDB |
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 8.0 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |