Molecule Details
| InChIKey | ZHIDWEDSQDSXBK-GZTJUZNOSA-N |
|---|---|
| Compound Name | ethyl 2-[(5E)-5-[[4-(4-bromopyrrolo[2,3-b]pyridin-1-yl)phenyl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetate |
| Canonical SMILES | CCOC(=O)CN1C(=O)S/C(=C/c2ccc(-n3ccc4c(Br)ccnc43)cc2)C1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.22 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43451 | MGAM | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| P10253 | GAA | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| P14410 | SI | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL |
| Q2M2H8 | MGAM2 | Homo sapiens | Human | PF13802 PF01055 PF21365 PF00088 | 6.3 | IC50 | ChEMBL;BindingDB |
| P0DUB6 | AMY1A | Homo sapiens | Human | PF00128 PF02806 | 6.1 | IC50 | ChEMBL |