Molecule Details
InChIKeyZHBAGBACXDDSPH-UHFFFAOYSA-N
Compound NameIndolocarbazole deriv. 14h
Canonical SMILESCn1ccc2ccc3c4[nH]c5c(CCCNCCO)cccc5c4c4c(c3c21)C(=O)NC4=O
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.69
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P11802 CDK4 Homo sapiens Human PF00069 7.6 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.6 IC50 ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.6 IC50 ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.6 IC50 ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.6 IC50 ChEMBL
Q9UQM7 CAMK2A Homo sapiens Human PF08332 PF00069 6.6 IC50 ChEMBL
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 pIC50 TTD_MultiTarget