N-[4-(1,3-benzothiazol-2-yl)-3-chlorophenyl]-7-methoxy-6-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine

InChIKey	`ZGTHJDQZGGIPLL-UHFFFAOYSA-N`
Compound Name	N-[4-(1,3-benzothiazol-2-yl)-3-chlorophenyl]-7-methoxy-6-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine
Canonical SMILES	`COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)c(Cl)c3)c2cc1OCCCN1CCN(C)CC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.68
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.4	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.4	pIC50	TTD_MultiTarget
Q02763	TEK	Homo sapiens	Human	PF00041 PF10430 PF07714	6.3	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	6.2	pIC50	TTD_MultiTarget
O14965	AURKA	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL;BindingDB