Molecule Details
| InChIKey | ZGEGOFCLSWVVKG-UHFFFAOYSA-N |
|---|---|
| Compound Name | Panadiplon |
| Canonical SMILES | CC(C)n1c(=O)c2c(-c3noc(C4CC4)n3)ncn2c2ccccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.88 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB21275 |
|---|---|
| Drug Name | Panadiplon |
| CAS Number | 124423-84-3 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Panadiplon is a small molecule drug. Panadiplon has a monoisotopic molecular weight of 335.14 Da. |
Categories: Heterocyclic Compounds, Fused-Ring Oxazoles
Cross-references: BindingDB: 50048837 CHEMBL279867 ZINC: ZINC000000004220
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 8.5 | Ki | ChEMBL;BindingDB |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL |
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL;BindingDB |
| P47870 | GABRB2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL |
| Q16445 | GABRA6 | Homo sapiens | Human | PF02931 PF02932 | 6.2 | Ki | ChEMBL;BindingDB |