Molecule Details
InChIKeyZGBGPEDJXCYQPH-UHFFFAOYSA-N
Compound NameAZ-628
Canonical SMILESCc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.0
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 7.7 IC50 ChEMBL;BindingDB
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 6.9 IC50 ChEMBL;BindingDB
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 6.4 IC50 ChEMBL;BindingDB