Molecule Details
| InChIKey | ZFZUYTCCHMWWTD-UHFFFAOYSA-N |
|---|---|
| Compound Name | spiro[2,4-dihydro-1H-naphthalene-3,4'-5H-1,3-oxazole]-2'-amine |
| Canonical SMILES | NC1=NC2(CCc3ccccc3C2)CO1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 9 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.64 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (9)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 9.2 | Ki | BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 9.0 | Ki | BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 8.8 | Ki | BindingDB |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 8.4 | Ki | BindingDB |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 7.7 | Ki | BindingDB |
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 7.6 | Ki | BindingDB |
| P07550 | ADRB2 | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P08588 | ADRB1 | Homo sapiens | Human | PF00001 | 6.0 | Ki | BindingDB |
| P23975 | SLC6A2 | Homo sapiens | Human | PF00209 | 6.0 | Ki | BindingDB |