tert-butyl N-[(2S)-1-[[(2S)-1-[[(1S,2S)-3-cyclohexyl-1-[(3S,5R)-5-ethenyl-1-methyl-2-oxopyrrolidin-3-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate

InChIKey	`ZFZUCSZEDBBENP-HPMAGDRPSA-N`
Compound Name	tert-butyl N-[(2S)-1-[[(2S)-1-[[(1S,2S)-3-cyclohexyl-1-[(3S,5R)-5-ethenyl-1-methyl-2-oxopyrrolidin-3-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Canonical SMILES	`C=C[C@H]1C[C@@H]([C@H](O)[C@H](CC2CCCCC2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C(=O)N1C`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	7.02
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00797	REN	Homo sapiens	Human	PF07966 PF00026	8.7	IC50	ChEMBL;BindingDB
P14091	CTSE	Homo sapiens	Human	PF07966 PF00026	6.8	IC50	ChEMBL;BindingDB
P07339	CTSD	Homo sapiens	Human	PF07966 PF00026	6.6	IC50	ChEMBL;BindingDB
P20142	PGC	Homo sapiens	Human	PF07966 PF00026	6.0	IC50	ChEMBL;BindingDB