Molecule Details
| InChIKey | ZFVRYNYOPQZKDG-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide |
| Canonical SMILES | CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(NC4CCC(O)CC4)c3)c2C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.3 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1 | Homo sapiens | Human | PF13589 PF00183 | 8.4 | IC50 | BindingDB |
| P08238 | HSP90AB1 | Homo sapiens | Human | PF13589 PF00183 | 8.4 | IC50 | BindingDB |
| P14625 | HSP90B1 | Homo sapiens | Human | PF13589 PF00183 | 6.3 | Kd | BindingDB |
| Q12931 | TRAP1 | Homo sapiens | Human | PF13589 PF00183 | 6.1 | IC50 | BindingDB |