Molecule Details
| InChIKey | ZEYYDOLCHFETHQ-JOCHJYFZSA-N |
|---|---|
| Canonical SMILES | O=C(O)[C@@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.7 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16346 |
|---|---|
| Drug Name | Veliflapon |
| CAS Number | 128253-31-6 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina). |
Categories: Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antirheumatic Agents Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Lipoxygenase Inhibitors Peripheral Nervous System Agents Sensory System Agents
Cross-references: BindingDB: 50052030 CHEMBL88712 ChemSpider: 110292 PDB: QY1 ZINC: ZINC000000598193
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P20292 | ALOX5AP | Arachidonate 5-lipoxygenase-activating protein | inhibitor | targets |