Molecule Details
| InChIKey | ZECOHPFWGOCWLO-UHFFFAOYSA-N |
|---|---|
| Compound Name | [4-[3-[[(4-chloro-1H-indazol-3-yl)amino]methyl]benzoyl]piperazin-1-yl]-(2,4-dichlorophenyl)methanone |
| Canonical SMILES | O=C(c1cccc(CNc2n[nH]c3cccc(Cl)c23)c1)N1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.45 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P53779 | MAPK10 | Homo sapiens | Human | PF00069 | 7.1 | IC50 | ChEMBL |
| Q9UKE5 | TNIK | Homo sapiens | Human | PF00780 PF00069 | 6.4 | IC50 | ChEMBL |
| P35916 | FLT4 | Homo sapiens | Human | PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 | 6.4 | IC50 | ChEMBL |
| O94806 | PRKD3 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 6.2 | IC50 | ChEMBL |
| Q8IVW4 | CDKL3 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |