Molecule Details
| InChIKey | ZDTUVVAJVVQVOT-UHFFFAOYSA-N |
|---|---|
| Compound Name | Synthesis of N-(2-fluorobenzyl)-6-(5-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide |
| Canonical SMILES | Cc1[nH]ncc1-c1ccc2cc(C(=O)NCc3ccccc3F)[nH]c2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.68 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 8.2 | IC50 | BindingDB |
| P51817 | PRKX | Homo sapiens | Human | PF00069 | 8.1 | IC50 | BindingDB |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.2 | IC50 | BindingDB |
| P17612 | PRKACA | Homo sapiens | Human | PF00069 | 7.2 | IC50 | BindingDB |