(1S,2R,4S)-N-(isoquinolin-3-yl)-4'H-4-azaspiro[bicyclo[2.2.2]octane-2,5'-oxazol]-2'-amine

InChIKey	`ZDTPXUKLGIDOCS-SFHVURJKSA-N`
Compound Name	(1S,2R,4S)-N-(isoquinolin-3-yl)-4'H-4-azaspiro[bicyclo[2.2.2]octane-2,5'-oxazol]-2'-amine
Canonical SMILES	`c1ccc2cc(NC3=NC[C@@]4(CN5CCC4CC5)O3)ncc2c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.61
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36544	CHRNA7	Homo sapiens	Human	PF02931 PF02932	8.9	Ki	ChEMBL
P46098	HTR3A	Homo sapiens	Human	PF02931 PF02932	6.3	IC50	ChEMBL