Molecule Details
InChIKeyZDACFCFMMWTLTA-STBZDDNXSA-N
Compound Name(4S,5R,6Z,9S,10S,12E)-9,10,18-trihydroxy-4,5-dimethyl-16-(methylamino)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione
Canonical SMILESCNc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\[C@@H](C)[C@H](C)OC2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.2
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q02750 MAP2K1 Homo sapiens Human PF00069 8.0 IC50 ChEMBL
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 7.6 IC50 ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 7.5 IC50 ChEMBL
Q13233 MAP3K1 Homo sapiens Human PF21040 PF00069 PF04434 7.3 IC50 ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 7.3 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 7.0 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.0 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.7 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.3 IC50 ChEMBL