Molecule Details
InChIKeyZCITXZXBLWIHHP-UHFFFAOYSA-N
Compound NameUS9493490, Example 4
Canonical SMILESCc1c(Oc2ccc(CN)cc2F)ccc2c1B(O)OC2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.42
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P17612 PRKACA Homo sapiens Human PF00069 8.4 IC50 BindingDB
Q15418 RPS6KA1 Homo sapiens Human PF00069 PF00433 8.3 IC50 ChEMBL;BindingDB
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 8.0 IC50 ChEMBL;BindingDB
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.7 IC50 ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 IC50 ChEMBL
P09211 GSTP1 Homo sapiens Human PF14497 PF02798 6.5 IC50 BindingDB