[4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-tetrahydro-furan-2-yl)-but-3-ynyl]-N-hydroxyurea

InChIKey	`ZBUWQTCXTJMDCD-UODIDJSMSA-N`
Compound Name	[4-((2S,5S)-5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-ylmethyl}-tetrahydro-furan-2-yl)-but-3-ynyl]-N-hydroxyurea
Canonical SMILES	`NC(=O)N(O)CCC#C[C@@H]1CC[C@@H](CN2CCN([C@H](c3ccccc3)c3ccc(Cl)cc3)CC2)O1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.9
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35367	HRH1	Homo sapiens	Human	PF00001	7.3	Ki	ChEMBL;BindingDB
P09917	ALOX5	Homo sapiens	Human	PF00305 PF01477	6.5	IC50	ChEMBL;BindingDB