Molecule Details
| InChIKey | ZBMZVLHSJCTVON-UHFFFAOYSA-N |
|---|---|
| Compound Name | Sotalol |
| Canonical SMILES | CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.35 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB00489 |
|---|---|
| Drug Name | Sotalol |
| CAS Number | 3930-20-9 |
| Groups | approved investigational |
| ATC Codes | C07AA07 C07BA07 C07FX02 |
| Description | Sotalol is a methanesulfonanilide developed in 1960.[A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992.[L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous inj... |
Categories: Adrenergic Agents Adrenergic Antagonists Adrenergic beta-Antagonists Agents causing hyperkalemia Alcohols Amines Amino Alcohols Antiarrhythmic agents Autonomic Agents Beta Blocking Agents and Thiazides Beta Blocking Agents, Non-Selective Beta Blocking Agents, Non-Selective, and Thiazides Bradycardia-Causing Agents Cardiac Rhythm Alteration Cardiovascular Agents Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index Cytochrome P-450 Substrates Ethanolamines Highest Risk QTc-Prolonging Agents Hypotensive Agents Narrow Therapeutic Index Drugs Neurotransmitter Agents Peripheral Nervous System Agents QTc Prolonging Agents Sympatholytics
Cross-references: BindingDB: 25762 ChEBI: 63622 CHEMBL471 ChemSpider: 5063 Drugs Product Database (DPD): 2048 C07309 PharmGKB: PA451457 PubChem:5253 PubChem:46505012 RxCUI: 9947 Therapeutic Targets Database: DAP000372 Wikipedia: Sotalol