[4-Amino-7-(Propan-2-Yl)-7h-Pyrrolo[2,3-D]pyrimidin-5-Yl](6-{[(3s,4r)-4-(4-Fluorophenyl)tetrahydrofuran-3-Yl]amino}pyrazin-2-Yl)methanone

InChIKey	`YXZBQCQAYNRRFP-IEBWSBKVSA-N`
Compound Name	[4-Amino-7-(Propan-2-Yl)-7h-Pyrrolo[2,3-D]pyrimidin-5-Yl](6-{[(3s,4r)-4-(4-Fluorophenyl)tetrahydrofuran-3-Yl]amino}pyrazin-2-Yl)methanone
Canonical SMILES	`CC(C)n1cc(C(=O)c2cncc(N[C@@H]3COC[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.37
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O15530	PDPK1	Homo sapiens	Human	PF14593 PF00069	9.2	Ki	ChEMBL;BindingDB
P31749	AKT1	Homo sapiens	Human	PF00169 PF00069 PF00433	6.6	Ki	ChEMBL;BindingDB
P42345	MTOR	Homo sapiens	Human	PF02259 PF02260 PF08771 PF23593 PF11865 PF00454	6.3	pIC50	TTD_MultiTarget