Molecule Details
| InChIKey | YXFPBFNFMATBRQ-BIHRQFPBSA-N |
|---|---|
| Compound Name | H-Arg-Gln-Phe-Arg-benzothiazol-2-yl |
| Canonical SMILES | N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)c1nc2ccccc2s1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.87 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y5Y6 | ST14 | Homo sapiens | Human | PF00431 PF00057 PF01390 PF00089 | 9.6 | Ki | ChEMBL;BindingDB |
| Q8IU80 | TMPRSS6 | Homo sapiens | Human | PF00057 PF01390 PF00089 | 8.8 | Ki | ChEMBL;BindingDB |
| O15393 | TMPRSS2 | Homo sapiens | Human | PF15494 PF00089 | 8.5 | IC50 | BindingDB |
| P05981 | HPN | Homo sapiens | Human | PF09272 PF00089 | 8.5 | Ki | BindingDB |