1-[3-(Pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)phenyl]-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1,3-thiazol-2-yl]urea

InChIKey	`YXEIECLOAMHVCH-UHFFFAOYSA-N`
Compound Name	1-[3-(Pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)phenyl]-3-[5-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)-1,3-thiazol-2-yl]urea
Canonical SMILES	`O=C(Nc1cc(CN2CCCC2)cc(C(F)(F)F)c1)Nc1ncc(CCNc2ncnc3ccsc23)s1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.15
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	8.4	IC50	ChEMBL
O75716	STK16	Homo sapiens	Human	PF00069	8.4	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB