Molecule Details
InChIKeyYWQFJBMWXOICTC-UHFFFAOYSA-N
Compound NameUS10233188, Example 145
Canonical SMILESCS(=O)(=O)N1CCC(Nc2ncc3cc(CCO)c(=O)n(C4CCCC4)c3n2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL8.13
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P11802 CDK4 Homo sapiens Human PF00069 9.3 Ki ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.8 Ki ChEMBL;BindingDB
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 8.8 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.8 Ki ChEMBL;BindingDB
Q00534 CDK6 Homo sapiens Human PF00069 8.8 Ki ChEMBL;BindingDB
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 6.9 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P06400 RB1 Homo sapiens Human PF11934 PF01858 PF01857 PF08934 6.6 IC50 ChEMBL