Molecule Details
InChIKeyYWFOHQFLGQVFIB-UHFFFAOYSA-N
Compound Name1-[2-(Diethylamino)ethyl]-3-[6-[5-[(4-fluorophenyl)sulfonylamino]-6-methoxy-3-pyridinyl]-1,3-benzothiazol-2-yl]urea
Canonical SMILESCCN(CC)CCNC(=O)Nc1nc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4)c3)cc2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.34
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P48736 PIK3CG Homo sapiens Human PF00454 PF00792 PF00794 PF00613 PF19710 8.0 IC50 ChEMBL
Q8WYR1 PIK3R5 Homo sapiens Human PF10486 8.0 IC50 ChEMBL
P42336 PIK3CA Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 7.9 IC50 ChEMBL
P42345 MTOR Homo sapiens Human PF02259 PF02260 PF08771 PF23593 PF11865 PF00454 7.1 IC50 ChEMBL;BindingDB
Q8N122 RPTOR Homo sapiens Human PF02985 PF14538 PF00400 7.1 IC50 ChEMBL
Q9BVC4 MLST8 Homo sapiens Human PF00400 7.1 IC50 ChEMBL
P27986 PIK3R1 Homo sapiens Human PF16454 PF00620 PF00017 7.0 IC50 ChEMBL;BindingDB
P42338 PIK3CB Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 7.0 IC50 ChEMBL
O00329 PIK3CD Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 6.8 IC50 ChEMBL