Molecule Details
InChIKeyYWCLDDLVLSQGSZ-JOCHJYFZSA-N
Compound NameS-3304
Canonical SMILESCc1ccc(C#Cc2ccc(S(=O)(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)O)s2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.3
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12149
Drug NameS-3304
CAS Number203640-27-1
Groups investigational
ATC Codes nan
DescriptionS-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non Small Cell Lung Cancer, among others.

Categories: Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Matrix Metalloproteinase Inhibitors Protease Inhibitors Sulfur Compounds
Cross-references: BindingDB: 50063129 CHEMBL297792 ChemSpider: 8894295 PubChem:10718956 PubChem:347828445
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P08253 MMP2 Homo sapiens Human PF00040 PF00045 PF00413 8.8 pIC50 TTD_MultiTarget
P14780 MMP9 Homo sapiens Human PF00040 PF00045 PF00413 7.8 IC50 ChEMBL;BindingDB