Molecule Details
| InChIKey | YVTHPCKJOKJJHA-UHFFFAOYSA-N |
|---|---|
| Compound Name | 12-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-6,11,17-triazatetracyclo[8.7.0.02,7.013,17]heptadeca-1(10),2(7),3,5,8,11,13,15-octaene |
| Canonical SMILES | c1cnc2ccc3nc(N4CCN(Cc5ccc6c(c5)OCO6)CC4)c4cccn4c3c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.55 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| A5X5Y0 | HTR3E | Homo sapiens | Human | PF02931 PF02932 | 7.5 | IC50 | ChEMBL |
| O95264 | HTR3B | Homo sapiens | Human | PF02931 PF02932 | 7.5 | IC50 | ChEMBL |
| P46098 | HTR3A | Homo sapiens | Human | PF02931 PF02932 | 7.5 | IC50 | ChEMBL;BindingDB |
| Q70Z44 | HTR3D | Homo sapiens | Human | PF02931 PF02932 | 7.5 | IC50 | ChEMBL |
| Q8WXA8 | HTR3C | Homo sapiens | Human | PF02931 PF02932 | 7.5 | IC50 | ChEMBL |