Molecule Details
InChIKeyYUSWMAULDXZHPY-UHFFFAOYSA-N
Compound NameAmentoflavone
Canonical SMILESO=c1cc(-c2ccc(O)c(-c3c(O)cc(O)c4c(=O)cc(-c5ccc(O)cc5)oc34)c2)oc2cc(O)cc(O)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)20
Pfam Stratification Cross-Family
Avg pChEMBL8.08
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (20)
Target Gene Organism Category Pfam pChEMBL Type Source
O00591 GABRP Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
O14764 GABRD Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P14867 GABRA1 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P18507 GABRG2 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P28472 GABRB3 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P31644 GABRA5 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P34903 GABRA3 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P47869 GABRA2 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P47870 GABRB2 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P48169 GABRA4 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P78334 GABRE Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
Q16445 GABRA6 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
Q8N1C3 GABRG1 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
Q99928 GABRG3 Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
Q9UN88 GABRQ Homo sapiens Human PF02931 PF02932 8.2 Ki ChEMBL
P49763 PGF Homo sapiens Human PF00341 8.1 Kd ChEMBL
P15692 VEGFA Homo sapiens Human PF00341 PF14554 7.8 Kd ChEMBL
P41143 OPRD1 Homo sapiens Human PF00001 7.4 Ki ChEMBL
P09874 PARP1 Homo sapiens Human PF00533 PF21728 PF00644 PF02877 PF05406 PF00645 PF08063 6.8 IC50 ChEMBL