Molecule Details
InChIKeyYUOWJICKAJQZLS-UHFFFAOYSA-N
Compound Name3-[(5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]propan-1-ol
Canonical SMILESOCCCNc1ncnc2[nH]cc(-c3ccccc3)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)35
Pfam Stratification Cross-Family
Avg pChEMBL6.43
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (35)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.7 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 7.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.2 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.9 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.8 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.8 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.7 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.6 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.6 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.6 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.4 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.2 Ki ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
O15111 CHUK Homo sapiens Human PF18397 PF12179 PF00069 6.1 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.1 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q14289 PTK2B Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.1 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P43405 SYK Homo sapiens Human PF07714 PF00017 6.0 Ki ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL