Molecule Details
InChIKeyYUDQXOMZBLEWBH-KAMYIIQDSA-N
Canonical SMILESCOc1ccccc1-c1ccc(NC(=O)/C(C#N)=C(/C)O)c(Cl)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.58
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08172
Drug Name(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: CHEMBL483161 ChemSpider: 24700256 PDB: MDY PubChem:54727975 PubChem:99444643 ZINC: ZINC000100036440
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q02127 DHODH Homo sapiens Human PF01180 7.2 IC50 ChEMBL
Q54A96 dhod Plasmodium falciparum Pathogen PF01180 6.0 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q02127 DHODH Dihydroorotate dehydrogenase (quinone), mitochondrial binder targets