Molecule Details
InChIKeyYTSDNPLOCDVGNB-UHFFFAOYSA-N
Compound Name3-(6-Methoxynaphthalen-2-Yl)-1-(Propan-2-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine
Canonical SMILESCOc1ccc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.1
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 7.1 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.4 IC50 ChEMBL;BindingDB
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.3 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.1 IC50 ChEMBL;BindingDB
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.1 IC50 ChEMBL;BindingDB
A3FQ16 Cryptosporidium parvum (strain Iowa II) Pathogen PF13499 PF00069 8.3 IC50 BindingDB
Q6S4W0 CDPK1 Cryptosporidium parvum Pathogen PF13499 PF00069 8.3 IC50 BindingDB
Q8MMZ7 PKG Toxoplasma gondii Pathogen PF00027 PF00069 8.2 IC50 BindingDB