Molecule Details
InChIKeyYTINZZFBHWSAGL-NDEPHWFRSA-N
Canonical SMILESN#Cc1ccc(N2CCN(Cc3ccc(COc4cccc5c4CN([C@H]4CCC(=O)NC4=O)C5=O)cc3)CC2)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.52
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB17584
Drug NameMezigdomide
CAS Number2259648-80-9
Groups investigational
ATC Codes nan
DescriptionMezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma).

Cross-references: CHEMBL4648616 ChemSpider: 84451594 PDB: QFC
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16531 DDB1 Homo sapiens Human PF10433 PF23726 PF03178 7.5 IC50 ChEMBL
Q96SW2 CRBN Homo sapiens Human PF02190 PF03226 7.5 IC50 ChEMBL