Molecule Details
| InChIKey | YSWYRVDXDMUHMQ-MSAZCCBOSA-N |
|---|---|
| Compound Name | (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-[(2S,3R)-3-hydroxy-4-[(6-methoxy-3-pyridinyl)sulfonyl-(2-methylpropyl)amino]-1-phenylbutan-2-yl]prop-2-enamide |
| Canonical SMILES | COc1ccc(S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)/C=C/c2cc(OC)c(O)c(OC)c2)cn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.54 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q72547 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00075 PF00078 PF06815 PF06817 | 7.9 | IC50 | ChEMBL;BindingDB |
| P04585 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 7.2 | IC50 | BindingDB |