Molecule Details
InChIKeyYSPIHUWHLMNFOV-JOCQHMNTSA-N
Canonical SMILESCn1ncc(-c2nc(N[C@H]3CC[C@H](N)CC3)ncc2F)c1CC1CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL8.04
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P50613 CDK7 Homo sapiens Human PF00069 9.5 Kd ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 8.3 Kd ChEMBL;BindingDB
Q14004 CDK13 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
O75909 CCNK Homo sapiens Human PF00134 PF21797 7.5 IC50 ChEMBL
Q9NYV4 CDK12 Homo sapiens Human PF00069 7.3 IC50 ChEMBL