Molecule Details
InChIKeyYRZKWAVVXPFIAT-SNAWJCMRSA-N
Compound NameUS12180207, Example 150
Canonical SMILESCOc1cc(-c2cnn(C3CN(C(=O)C4CN(C(=O)/C=C/CN(C)C)C4)C3)c2)cn2ncc(C#N)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.83
SourceBindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P21802 FGFR2 Homo sapiens Human PF07679 PF13927 PF07714 8.2 IC50 BindingDB
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 7.9 IC50 BindingDB
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 7.4 IC50 BindingDB