Molecule Details
InChIKeyYRMCFRAIIGMZRN-UHFFFAOYSA-N
Compound NameUS11472791, Example 39
Canonical SMILESN#Cc1cnc(NC2CCN(S(=O)(=O)c3ccccn3)CC2)nc1-c1cnn(CC(F)(F)F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.43
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 9.5 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.3 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.8 IC50 ChEMBL
P30281 CCND3 Homo sapiens Human PF02984 PF00134 7.8 IC50 ChEMBL
Q00534 CDK6 Homo sapiens Human PF00069 7.8 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 7.0 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.1 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 6.1 IC50 ChEMBL
P51948 MNAT1 Homo sapiens Human PF25811 PF06391 PF17121 6.1 IC50 ChEMBL