Molecule Details
InChIKeyYRDHKIFCGOZTGD-UHFFFAOYSA-N
Compound NameXmu-MP-1
Canonical SMILESCN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)21
Pfam Stratification Cross-Family
Avg pChEMBL7.34
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (21)
Target Gene Organism Category Pfam pChEMBL Type Source
O14965 AURKA Homo sapiens Human PF00069 7.8 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.8 IC50 ChEMBL
P48736 PIK3CG Homo sapiens Human PF00454 PF00792 PF00794 PF00613 PF19710 7.8 IC50 ChEMBL
Q9P289 STK26 Homo sapiens Human PF20929 PF00069 7.7 IC50 ChEMBL
O15075 DCLK1 Homo sapiens Human PF03607 PF00069 7.6 IC50 ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.6 IC50 ChEMBL
Q9Y6E0 STK24 Homo sapiens Human PF20929 PF00069 7.5 IC50 ChEMBL
P23458 JAK1 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.5 IC50 ChEMBL
Q99759 MAP3K3 Homo sapiens Human PF00564 PF00069 7.5 IC50 ChEMBL
P42336 PIK3CA Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 7.5 Kd ChEMBL
Q8TBX8 PIP4K2C Homo sapiens Human PF01504 7.5 Kd ChEMBL
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.4 IC50 ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 7.4 IC50 ChEMBL
Q8IYT8 ULK2 Homo sapiens Human PF12063 PF21127 PF00069 7.4 IC50 ChEMBL
Q9Y2U5 MAP3K2 Homo sapiens Human PF00564 PF00069 7.4 IC50 ChEMBL
Q13043 STK4 Homo sapiens Human PF11629 PF00069 7.2 IC50 ChEMBL
Q9UL54 TAOK2 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P57078 RIPK4 Homo sapiens Human PF12796 PF13637 PF00069 6.8 Kd ChEMBL
Q7L7X3 TAOK1 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
O60331 PIP5K1C Homo sapiens Human PF01504 6.7 IC50 ChEMBL
Q9H2K8 TAOK3 Homo sapiens Human PF00069 6.4 IC50 ChEMBL