2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide

InChIKey	`YRAPNFDLJRSFKB-UHFFFAOYSA-N`
Compound Name	2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide
Canonical SMILES	`Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5csc(C)n5)c4)CC3)cccc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	8.38
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P28221	HTR1D	Homo sapiens	Human	PF00001	9.4	Ki	ChEMBL
P08908	HTR1A	Homo sapiens	Human	PF00001	9.1	Ki	ChEMBL
P28222	HTR1B	Homo sapiens	Human	PF00001	8.5	Ki	ChEMBL
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	6.5	Ki	ChEMBL;BindingDB