Molecule Details
| InChIKey | YQBNFYFUPHSRMR-UHFFFAOYSA-N |
|---|---|
| Compound Name | US11407757, Cpd 71 |
| Canonical SMILES | CCN1CCN(Cc2ccc(Nc3nc(OCCOC)c4c(-c5ccc(F)c(Cl)c5)c[nH]c4n3)cc2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.85 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P30530 | AXL | Homo sapiens | Human | PF00041 PF13927 PF07714 | 7.2 | IC50 | ChEMBL;BindingDB |
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 7.2 | IC50 | ChEMBL;BindingDB |
| P08581 | MET | Homo sapiens | Human | PF07714 PF01437 PF01403 PF01833 | 6.2 | IC50 | ChEMBL;BindingDB |