Molecule Details
| InChIKey | YPMBTZWFMDTVIO-JTQLQIEISA-N |
|---|---|
| Compound Name | 1,1-dioxo-2-[[(5S)-3-thiophen-2-yl-4,5-dihydro-1,2-oxazol-5-yl]methyl]-1,2-benzothiazol-3-one |
| Canonical SMILES | O=C1c2ccccc2S(=O)(=O)N1C[C@@H]1CC(c2cccs2)=NO1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.98 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 9.0 | Ki | ChEMBL;BindingDB |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 8.6 | Ki | ChEMBL;BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.9 | Ki | ChEMBL;BindingDB |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 6.4 | Ki | ChEMBL;BindingDB |