Molecule Details
| InChIKey | YOJLXUCTDDKMGX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(3,4-Dimethoxyphenyl)sulfanyl-5-methylthieno[2,3-d]pyrimidine-2,4-diamine |
| Canonical SMILES | COc1ccc(Sc2sc3nc(N)nc(N)c3c2C)cc1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.31 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00374 | DHFR | Homo sapiens | Human | PF00186 | 6.0 | IC50 | ChEMBL;BindingDB |
| A0A0W4ZHR8 | Pneumocystis jirovecii (strain RU7) | Pathogen | PF00186 | 6.6 | IC50 | BindingDB |