Molecule Details
InChIKeyYNZFUWZUGRBMHL-UHFFFAOYSA-N
Compound NameOpipramol
Canonical SMILESOCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.45
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12930
Drug NameOpipramol
CAS Number315-72-0
Groups investigational
ATC Codes N06AA05
DescriptionOpipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

Categories: Adrenergic Agents Agents that produce hypertension Agents that reduce seizure threshold Antidepressive Agents Antidepressive Agents, Tricyclic Central Nervous System Agents Central Nervous System Depressants Dibenzazepines Heterocyclic Compounds, Fused-Ring Membrane Transport Modulators Narrow Therapeutic Index Drugs Nervous System Neurotoxic agents Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Non-Selective Monoamine Reuptake Inhibitors Psychoanaleptics Psychotropic Drugs Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
Cross-references: BindingDB: 50170636 ChEBI: 94614 CHEMBL370753 ChemSpider: 9046 PharmGKB: PA144614922 PubChem:9417 PubChem:347829075 RxCUI: 7674 Wikipedia: Opipramol ZINC: ZINC000021981303
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q99720 SIGMAR1 Homo sapiens Human PF04622 9.7 Ki ChEMBL;BindingDB
Q15125 EBP Homo sapiens Human PF05241 7.9 Ki ChEMBL;BindingDB
P32352 ERG2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Pathogen PF04622 7.8 Ki ChEMBL;BindingDB