1-(4-acetylphenyl)-3-(2-aminoquinazolin-6-yl)-4-methylpyridin-2(1H)-one

InChIKey	`YNVQXAFBFLYMLM-UHFFFAOYSA-N`
Compound Name	1-(4-acetylphenyl)-3-(2-aminoquinazolin-6-yl)-4-methylpyridin-2(1H)-one
Canonical SMILES	`CC(=O)c1ccc(-n2ccc(C)c(-c3ccc4nc(N)ncc4c3)c2=O)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.75
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	7.6	IC50	ChEMBL;BindingDB
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.4	IC50	ChEMBL;BindingDB
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.2	IC50	ChEMBL;BindingDB