Molecule Details
| InChIKey | YNUMBZPWLHDVEX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(6-Cyano-2-pyridinyl)-3-[7-(trifluoromethyl)quinolin-4-yl]urea |
| Canonical SMILES | N#Cc1cccc(NC(=O)Nc2ccnc3cc(C(F)(F)F)ccc23)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.88 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 7.6 | Ki | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 7.4 | Ki | ChEMBL |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.1 | Ki | ChEMBL |
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.7 | Ki | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 6.5 | Ki | ChEMBL |
| P48729 | CSNK1A1 | Homo sapiens | Human | PF00069 | 6.0 | Ki | ChEMBL |