Molecule Details
| InChIKey | YNADXFWEXJTQSZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | TC-E 5005 |
| Canonical SMILES | CCCc1nc(C)c2c(C)nc3ccc(OC)nc3n12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.69 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 8.0 | IC50 | ChEMBL;BindingDB |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q9HCR9 | PDE11A | Homo sapiens | Human | PF01590 PF00233 | 6.1 | IC50 | ChEMBL;BindingDB |
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 6.0 | IC50 | ChEMBL;BindingDB |