Molecule Details
| InChIKey | YMQVTFAERCACRG-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(4-Benzylpiperazin-1-yl)-8-chloropyrrolo[1,2-a]quinoxaline |
| Canonical SMILES | Clc1ccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.69 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P46098 | HTR3A | Homo sapiens | Human | PF02931 PF02932 | 7.7 | IC50 | ChEMBL;BindingDB |
| A5X5Y0 | HTR3E | Homo sapiens | Human | PF02931 PF02932 | 7.7 | IC50 | ChEMBL |
| O95264 | HTR3B | Homo sapiens | Human | PF02931 PF02932 | 7.7 | IC50 | ChEMBL |
| Q70Z44 | HTR3D | Homo sapiens | Human | PF02931 PF02932 | 7.7 | IC50 | ChEMBL |
| Q8WXA8 | HTR3C | Homo sapiens | Human | PF02931 PF02932 | 7.7 | IC50 | ChEMBL |