Molecule Details
| InChIKey | YMNHISNDWVXKND-UHFFFAOYSA-N |
|---|---|
| Compound Name | 7-Morpholin-4-yl-4-(propan-2-ylamino)cinnoline-3-carboxamide |
| Canonical SMILES | CC(C)Nc1c(C(N)=O)nnc2cc(N3CCOCC3)ccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.43 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q5S007 | LRRK2 | Homo sapiens | Human | PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 | 8.1 | IC50 | ChEMBL;BindingDB |
| P07333 | CSF1R | Homo sapiens | Human | PF00047 PF25305 PF07714 | 7.7 | IC50 | ChEMBL;BindingDB |
| P16234 | PDGFRA | Homo sapiens | Human | PF07679 PF25305 PF07714 | 6.6 | IC50 | ChEMBL;BindingDB |