Molecule Details
| InChIKey | YMHOBZXQZVXHBM-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-Bromo-2,5-Dimethoxyphenethylamine |
| Canonical SMILES | COc1cc(CCN)c(OC)cc1Br |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 13 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.93 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01537 |
|---|---|
| Drug Name | 4-Bromo-2,5-dimethoxyphenethylamine |
| CAS Number | 66142-81-2 |
| Groups | illicit investigational |
| ATC Codes | nan |
| Description | nan |
Categories: Adrenergic Agents Adrenergic Agonists Adrenergic alpha-1 Receptor Agonists Adrenergic alpha-Agonists Amines Antidepressive Agents Central Nervous System Depressants Ethylamines Neurotransmitter Agents Phenethylamines Serotonin Agents
Cross-references: BindingDB: 50005267 ChEBI: 189669 CHEMBL292821 ChemSpider: 88978 PubChem:98527 PubChem:46504806 Wikipedia: 4-Bromo-2,5-dimethoxyphenethylamine ZINC: ZINC000002564752
Target Activities (13)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL;BindingDB |
| P41595 | HTR2B | Homo sapiens | Human | PF00001 | 7.9 | Ki | BindingDB |
| P28221 | HTR1D | Homo sapiens | Human | PF00001 | 7.6 | Ki | BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 7.0 | Ki | BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 7.0 | Ki | BindingDB |
| P28222 | HTR1B | Homo sapiens | Human | PF00001 | 7.0 | Ki | BindingDB |
| P28566 | HTR1E | Homo sapiens | Human | PF00001 | 6.9 | Ki | BindingDB |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 6.7 | Ki | BindingDB |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 6.6 | Ki | BindingDB |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 6.5 | Ki | BindingDB |
| P50406 | HTR6 | Homo sapiens | Human | PF00001 | 6.5 | Ki | BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 6.2 | Ki | BindingDB |
| P20309 | CHRM3 | Homo sapiens | Human | PF00001 | 6.1 | Ki | BindingDB |