((2R,5S)-5-{2-[(1R)-1-Hydroxyethyl]-1H-imidazo[4,5-d]thieno[3,2-b]pyridin-1-yl}tetrahydro-2H-pyran-2-yl)acetonitrile

InChIKey	`YMFIMTJNSGCVCV-GRYCIOLGSA-N`
Compound Name	((2R,5S)-5-{2-[(1R)-1-Hydroxyethyl]-1H-imidazo[4,5-d]thieno[3,2-b]pyridin-1-yl}tetrahydro-2H-pyran-2-yl)acetonitrile
Canonical SMILES	`C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)OC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.67
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P23458	JAK1	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.9	IC50	ChEMBL;BindingDB
O00329	PIK3CD	Homo sapiens	Human	PF00454 PF00792 PF02192 PF00794 PF00613	6.6	IC50	ChEMBL;BindingDB
Q06418	TYRO3	Homo sapiens	Human	PF00041 PF07679 PF07714	6.5	IC50	ChEMBL;BindingDB